Our Knights Inn Santee hotel is conveniently located right off I-95, just down the road from the sprawling Santee State Park and Lake Marion South Carolina's largest lake. Our pet-friendly hotel puts you within minutes of restaurants and popular attractions along the Santee River Valley. Play a round of 18 at one of 3 golf courses in town: Santee National Golf Club, Santee Cooper Country Golf Club, and Lake Marion Golf Course. We're also set directly between Charleston and Columbia, so you can visit either city with ease.
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