Kirkwood Presbyterian hosts Sunday school classes for children and adults and bible studie. It also serves as a meeting place for such groups as Alcoholics Anonymous, Al-Anon, Ala-Teen, Crafty Ladies, Boy Scouts, Cub Scouts, a youth group and more. Church members have established a Good Samaritan Fund for those in need and take part in local and global missions. There are also several choirs, and the church hosts a concert series.